Protein Name:
Dipeptidyl peptidase 1
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UniprotKB/SwissProt ID: P53634 (P53634)
Gene Name:
CTSC
Organism: Homo sapiens (Human)
Function: Thiol protease (PubMed:1586157). Has dipeptidylpeptidase activity (PubMed:1586157). Active against a broad range of dipeptide substrates composed of both polar and hydrophobic amino acids (PubMed:1586157). Proline cannot occupy the P1 position and arginine cannot occupy the P2 position of the substrate (PubMed:1586157). Can act as both an exopeptidase and endopeptidase (PubMed:1586157). Activates serine proteases such as elastase, cathepsin G and granzymes A and B (PubMed:8428921)
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Lysosome
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Graphical Visualization of S-nitrosylation Sites:
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The S-nitrosylation sites of P53634
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| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
136 |
VHDVLGRNWA C FTGKKVGTAS |
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| 2 |
258 |
PVRNQASCGS C YSFASMGMLE |
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| 3 |
331 |
CFPYTGTDSP C KMKEDCFRYY |
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| 4 |
448 |
YFRIRRGTDE C AIESIAVAAT |
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