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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Actin-7

UniprotKB/SwissProt ID: P53492 (P53492)

Gene Name: ACT7

Organism: Arabidopsis thaliana (Mouse-ear cress)

Function: Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells (PubMed:11449050). Essential component of cell cytoskeleton; plays an important role in cytoplasmic streaming, cell shape determination, cell division, organelle movement and extension growth (PubMed:11449050). This is considered as one of the vegetative actins which is involved in the regulation of hormone-induced plant cell proliferation and callus formation (PubMed:11449050). Required for the trafficking and endocytic recycling of ABCG36/PEN3 between the trans-Golgi network and the plasma membrane in root epidermal and cap cells (PubMed:27803190)

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cytoplasm, cytoskeleton

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR004000 Actin
IPR020902 Actin/actin-like_CS
IPR004001 Actin_CS
IPR043129 ATPase_NBD

The S-nitrosylation sites of P53492

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 12 ADGEDIQPLV C DNGTGMVKAG   
2 259 VITIGAERFR C PEVLFQPSLI   
3 287 HETTYNSIMK C DVDIRKDLYG