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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Arf-GAP domain and FG repeat-containing protein 1

UniprotKB/SwissProt ID: P52594 (P52594)

Gene Name: AGFG1

Organism: Homo sapiens (Human)

Function: Required for vesicle docking or fusion during acrosome biogenesis (By similarity). May play a role in RNA trafficking or localization. In case of infection by HIV-1, acts as a cofactor for viral Rev and promotes movement of Rev-responsive element-containing RNAs from the nuclear periphery to the cytoplasm. This step is essential for HIV-1 replication

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Nucleus. Cytoplasmic vesicle

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR052248 Arf-GAP_FG-repeat_protein
IPR037278 ARFGAP/RecO
IPR001164 ArfGAP_dom
IPR038508 ArfGAP_dom_sf

The S-nitrosylation sites of P52594

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 52 MTVGSFVCTS C SGSLRGLNPP