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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Rho GDP-dissociation inhibitor 2

UniprotKB/SwissProt ID: P52566 (P52566)

Gene Name: ARHGDIB

Organism: Homo sapiens (Human)

Function: Regulates the GDP/GTP exchange reaction of the Rho proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP to them (PubMed:7512369, PubMed:8356058). Regulates reorganization of the actin cytoskeleton mediated by Rho family members (PubMed:8262133)

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cytoplasm, cytosol

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR014756 Ig_E-set
IPR000406 Rho_GDI
IPR024792 RhoGDI_dom_sf

The S-nitrosylation sites of P52566

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 76 NVVVTRLTLV C ESAPGPITMD  CCCCCCCCCC C CCCCCCCHHH  3.73% 25040305