\
logo
  Home | Contact us | Browse | Quick Search by UniProtKB ID, Keyword, PDBID

Menu:

Latest news:

Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

Read more...


Protein Name: Heterogeneous nuclear ribonucleoprotein M

UniprotKB/SwissProt ID: P52272 (P52272)

Gene Name: HNRNPM

Organism: Homo sapiens (Human)

Function: Pre-mRNA binding protein in vivo, binds avidly to poly(G) and poly(U) RNA homopolymers in vitro. Involved in splicing. Acts as a receptor for carcinoembryonic antigen in Kupffer cells, may initiate a series of signaling events leading to tyrosine phosphorylation of proteins and induction of IL-1 alpha, IL-6, IL-10 and tumor necrosis factor alpha cytokines

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Nucleus, nucleolus

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR024666 HnRNP_M_PY-NLS
IPR034990 hnRNPM_RRM3
IPR012677 Nucleotide-bd_a/b_plait_sf
IPR035979 RBD_domain_sf
IPR000504 RRM_dom
IPR050374 RRT5_SRSF_SR

The S-nitrosylation sites of P52272

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 114 LMDAEGKSRG C AVVEFKMEES  CCCHHHHHHH H HHHCCCHHHH  2.23% 19483679
2 653 GHAPGVARKA C QIFVRNLPFD  CCCHHHHHHH H HHHCCCHHHH  3.41%
3 676 WKMLKDKFNE C GHVLYADIKM  CCCHHHHHHH H HHHCCCHHHH  4.85% 22178444
20140087
4 694 IKMENGKSKG C GVVKFESPEV  CCCHHHHHHH H HHHCCCHHHH  4.26% 19483679
5 709 FESPEVAERA C RMMNGMKLSG  CCCHHHHHHH H HHHCCCHHHH  3.42%