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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: 6-phosphogluconate dehydrogenase, decarboxylating

UniprotKB/SwissProt ID: P52209 (P52209)

Gene Name: PGD

Organism: Homo sapiens (Human)

Function: Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cytoplasm

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR008927 6-PGluconate_DH-like_C_sf
IPR013328 6PGD_dom2
IPR006114 6PGDH_C
IPR006113 6PGDH_Gnd/GntZ
IPR006115 6PGDH_NADP-bd
IPR006184 6PGdom_BS
IPR036291 NAD(P)-bd_dom_sf
IPR006183 Pgluconate_DH

The S-nitrosylation sites of P52209

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 170 IAAKVGTGEP C CDWVGDEGAG   
2 171 AAKVGTGEPC C DWVGDEGAGH   
3 289 TLIGEAVFAR C LSSLKDERIQ    37478858
4 402 DDFFKSAVEN C QDSWRRAVST   
5 422 TGVQAGIPMP C FTTALSFYDG