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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Teratocarcinoma-derived growth factor

UniprotKB/SwissProt ID: P51865 (P51865)

Gene Name: Cripto

Organism: Mus musculus (Mouse)

Function: GPI-anchored cell membrane protein involved in Nodal signaling. Cell-associated CRIPTO acts as a Nodal coreceptor in cis. Shedding of CRIPTO by Tmem8a modulates Nodal signaling by allowing soluble CRIPTO to act as a Nodal coreceptor on other cells. Could play a role in the determination of the epiblastic cells that subsequently give rise to the mesoderm

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cell membrane. Secreted

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR017047 Cripto_growth_factor
IPR019011 Cryptic/Cripto_CFC-dom
IPR000742 EGF-like_dom