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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: H(+)/Cl(-) exchange transporter 5

UniprotKB/SwissProt ID: P51796 (P51796)

Gene Name: Clcn5

Organism: Rattus norvegicus (Rat)

Function: Proton-coupled chloride transporter. Functions as antiport system and exchanges chloride ions against protons. Important for normal acidification of the endosome lumen. May play an important role in renal tubular function (By similarity). The CLC channel family contains both chloride channels and proton-coupled anion transporters that exchange chloride or another anion for protons. The absence of conserved gating glutamate residues is typical for family members that function as channels (Probable)

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Golgi apparatus membrane. Endosome membrane. Cell membrane

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR000644 CBS_dom
IPR046342 CBS_dom_sf
IPR014743 Cl-channel_core
IPR002247 Cl_channel-5
IPR001807 ClC

The S-nitrosylation sites of P51796

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 414 ALFIRTNIAW C RKRKTTQLGK