Protein Name:
Dual specificity protein phosphatase 3
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UniprotKB/SwissProt ID: P51452 (P51452)
Gene Name:
DUSP3
Organism: Homo sapiens (Human)
Function: Shows activity both for tyrosine-protein phosphate and serine-protein phosphate, but displays a strong preference toward phosphotyrosines (PubMed:10224087, PubMed:11863439). Specifically dephosphorylates and inactivates ERK1 and ERK2 (PubMed:10224087, PubMed:11863439)
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Nucleus. Cytoplasm, cytoskeleton, flagellum axoneme
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Graphical Visualization of S-nitrosylation Sites:
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The S-nitrosylation sites of P51452
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| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
124 |
AQKNGRVLVH C REGYSRSPTL |
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| 2 |
171 |
GPNDGFLAQL C QLNDRLAKEG |
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