Protein Name:
Long-chain specific acyl-CoA dehydrogenase, mitochondrial
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UniprotKB/SwissProt ID: P51174 (P51174)
Gene Name:
Acadl
Organism: Mus musculus (Mouse)
Function: Long-chain specific acyl-CoA dehydrogenase is one of the acyl-CoA dehydrogenases that catalyze the first step of mitochondrial fatty acid beta-oxidation, an aerobic process breaking down fatty acids into acetyl-CoA and allowing the production of energy from fats. The first step of fatty acid beta-oxidation consists in the removal of one hydrogen from C-2 and C-3 of the straight-chain fatty acyl-CoA thioester, resulting in the formation of trans-2-enoyl-CoA (By similarity). Among the different mitochondrial acyl-CoA dehydrogenases, long-chain specific acyl-CoA dehydrogenase can act on saturated and unsaturated acyl-CoAs with 6 to 24 carbons with a preference for 8 to 18 carbons long primary chains (PubMed:9861014)
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Mitochondrion matrix
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Graphical Visualization of S-nitrosylation Sites:
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The S-nitrosylation sites of P51174
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| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
166 |
KFIPQMTAGK C IGAIAMTEPG |
CHHHHHHHHH H HHHHHCCCCC |
3.2% |
22178444
21278135
23748021
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| 2 |
303 |
LLIAELAISA C EFMFEETRNY |
CHHHHHHHHH H HHHHHCCCCC |
3.1% |
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| 3 |
342 |
HKLAELKTHI C VTRAFVDSCL |
CHHHHHHHHH H HHHHHCCCCC |
1.66% |
22178444
21278135
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| 4 |
351 |
ICVTRAFVDS C LQLHETKRLD |
CHHHHHHHHH H HHHHHCCCCC |
2.13% |
21278135
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| 5 |
383 |
SELQNSVAYE C VQLHGGWGYM |
CHHHHHHHHH H HHHHHCCCCC |
1.22% |
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