Protein Name:
Very long-chain specific acyl-CoA dehydrogenase, mitochondrial
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UniprotKB/SwissProt ID: P50544 (P50544)
Gene Name:
Acadvl
Organism: Mus musculus (Mouse)
Function: Very long-chain specific acyl-CoA dehydrogenase is one of the acyl-CoA dehydrogenases that catalyze the first step of mitochondrial fatty acid beta-oxidation, an aerobic process breaking down fatty acids into acetyl-CoA and allowing the production of energy from fats. The first step of fatty acid beta-oxidation consists in the removal of one hydrogen from C-2 and C-3 of the straight-chain fatty acyl-CoA thioester, resulting in the formation of trans-2-enoyl-CoA. Among the different mitochondrial acyl-CoA dehydrogenases, very long-chain specific acyl-CoA dehydrogenase acts specifically on acyl-CoAs with saturated 12 to 24 carbons long primary chains
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Mitochondrion inner membrane
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Graphical Visualization of S-nitrosylation Sites:
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The S-nitrosylation sites of P50544
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| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
216 |
VASGQALAAF C LTEPSSGSDV |
CCCCCCCHHH H HHHHHHCCCC |
3.84% |
21278135
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| 2 |
238 |
SIRSSAIPSP C GKYYTLNGSK |
CCCCCCCHHH H HHHHHHCCCC |
9.6% |
23281369
21278135
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| 3 |
423 |
QIEAAISKIF C SEAAWKVADE |
CCCCCCCHHH H HHHHHHCCCC |
4.01% |
21278135
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| 4 |
434 |
SEAAWKVADE C IQIMGGMGFM |
CCCCCCCHHH H HHHHHHCCCC |
2.6% |
21278135
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| 5 |
478 |
ILRLFVALQG C MDKGKELTGL |
CCCCCCCHHH H HHHHHHCCCC |
1.74% |
21278135
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| 6 |
604 |
YPTAQHEKML C DSWCIEAATR |
CCCCCCCHHH H HHHHHHCCCC |
3.31% |
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| 7 |
608 |
QHEKMLCDSW C IEAATRIREN |
CCCCCCCHHH H HHHHHHCCCC |
2.03% |
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