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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Pulmonary surfactant-associated protein D

UniprotKB/SwissProt ID: P50404 (P50404)

Gene Name: Sftpd

Organism: Mus musculus (Mouse)

Function: Contributes to the lung's defense against inhaled microorganisms, organic antigens and toxins. Interacts with compounds such as bacterial lipopolysaccharides, oligosaccharides and fatty acids and modulates leukocyte action in immune response. May participate in the extracellular reorganization or turnover of pulmonary surfactant. Binds strongly maltose residues and to a lesser extent other alpha-glucosyl moieties

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Secreted, extracellular space, extracellular matrix. Secreted, extracellular space, surface film

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR001304 C-type_lectin-like
IPR016186 C-type_lectin-like/link_sf
IPR018378 C-type_lectin_CS
IPR051077 Ca-dependent_lectin
IPR008160 Collagen
IPR033990 Collectin_CTLD
IPR016187 CTDL_fold
IPR015097 Surfac_D-trimer

The S-nitrosylation sites of P50404

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 34 SLSQRSVPNT C TLVMCSPTEN  CCHHHHHHHH H HHHHCHHHHH  3.35%
2 39 SVPNTCTLVM C SPTENGLPGR  CCHHHHHHHH H HHHHCHHHHH  3.25%