Protein Name:
Rab GDP dissociation inhibitor beta
|
UniprotKB/SwissProt ID: P50395 (P50395)
Gene Name:
GDI2
Organism: Homo sapiens (Human)
Function: GDP-dissociation inhibitor preventing the GDP to GTP exchange of most Rab proteins. By keeping these small GTPases in their inactive GDP-bound form regulates intracellular membrane trafficking (PubMed:25860027). Negatively regulates protein transport to the cilium and ciliogenesis through the inhibition of RAB8A (PubMed:25860027)
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Cytoplasm. Membrane. Golgi apparatus, trans-Golgi network
|
|
|
Graphical Visualization of S-nitrosylation Sites:
|
|
The S-nitrosylation sites of P50395
|
| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
202 |
YRTDDYLDQP C YETINRIKLY |
CCCCCCEEEE C CCHHHHHHHC |
3.89% |
18335467
|
| 2 |
282 |
GEIARCKQLI C DPSYVKDRVE |
CCCCCCEEEE C CCHHHHHHHC |
9.52% |
|
| 3 |
302 |
EKVGQVIRVI C ILSHPIKNTN |
CCCCCCEEEE C CCHHHHHHHC |
2.04% |
|
| 4 |
317 |
PIKNTNDANS C QIIIPQNQVN |
CCCCCCEEEE C CCHHHHHHHC |
3.19% |
|
| 5 |
335 |
QVNRKSDIYV C MISFAHNVAA |
CCCCCCEEEE C CCHHHHHHHC |
0.82% |
37478858
|
| 6 |
414 |
YDATTHFETT C DDIKNIYKRM |
CCCCCCEEEE C CCHHHHHHHC |
6.05% |
37478858
|
|
