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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Neuropeptide Y receptor type 4

UniprotKB/SwissProt ID: P50391 (P50391)

Gene Name: NPY4R

Organism: Homo sapiens (Human)

Function: G protein-coupled receptor for PPY/pancreatic polypeptide/PP, NPY/neuropeptide Y and PYY/peptide YY that is negatively coupled to cAMP (PubMed:7493937, PubMed:7592911). The rank order of affinity for these polypeptides and their derivatives is PP, PP (2-36) and [Ile-31, Gln-34] PP > [Pro-34] PYY > PYY and [Leu-31, Pro-34] NPY > NPY > PYY (3-36) and NPY (2-36) > PP (13-36) > PP (31-36) > NPY free acid

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cell membrane

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR000276 GPCR_Rhodpsn
IPR017452 GPCR_Rhodpsn_7TM
IPR001933 NPY4_rcpt
IPR000611 NPY_rcpt