Protein Name:
NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial
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UniprotKB/SwissProt ID: P49821 (P49821)
Gene Name:
NDUFV1
Organism: Homo sapiens (Human)
Function: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor (PubMed:28844695). Part of the peripheral arm of the enzyme, where the electrons from NADH are accepted by flavin mononucleotide (FMN) and then passed along a chain of iron-sulfur clusters by electron tunnelling to the final acceptor ubiquinone (PubMed:28844695). Contains FMN, which is the initial electron acceptor as well as one iron-sulfur cluster (PubMed:28844695)
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Mitochondrion inner membrane
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Graphical Visualization of S-nitrosylation Sites:
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The S-nitrosylation sites of P49821
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| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
125 |
VNADEGEPGT C KDREILRHDP |
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| 2 |
142 |
RHDPHKLLEG C LVGGRAMGAR |
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| 3 |
187 |
YEAGLIGKNA C GSGYDFDVFV |
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| 4 |
206 |
FVVRGAGAYI C GEETALIESI |
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| 5 |
425 |
ISKQIEGHTI C ALGDGAAWPV |
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