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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Regulator of G-protein signaling 10

UniprotKB/SwissProt ID: P49806 (P49806)

Gene Name: Rgs10

Organism: Rattus norvegicus (Rat)

Function: Regulates G protein-coupled receptor signaling cascades, including signaling downstream of the muscarinic acetylcholine receptor CHRM2. Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP-bound form. Modulates the activity of potassium channels that are activated in response to CHRM2 signaling. Activity on GNAZ is inhibited by palmitoylation of the G-protein

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cytoplasm, cytosol. Nucleus

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR016137 RGS
IPR046995 RGS10/12/14-like
IPR037879 RGS10_RGS
IPR036305 RGS_sf
IPR024066 RGS_subdom1/3
IPR044926 RGS_subdomain_2