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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Nuclear pore complex protein Nup98-Nup96

UniprotKB/SwissProt ID: P49793 (P49793)

Gene Name: Nup98

Organism: Rattus norvegicus (Rat)

Function: Plays a role in the nuclear pore complex (NPC) assembly and/or maintenance. Involved in the bidirectional transport across the NPC. May anchor NUP153 and TPR to the NPC Plays a role in the nuclear pore complex (NPC) assembly and/or maintenance. NUP98 and NUP96 are involved in the bidirectional transport across the NPC. May anchor NUP153 and TPR to the NPC. In cooperation with DHX9, plays a role in transcription and alternative splicing activation of a subset of genes. Involved in the localization of DHX9 in discrete intranuclear foci (GLFG-body)

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Nucleus membrane. Nucleus, nuclear pore complex. Nucleus, nucleoplasm

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR037665 Nucleoporin_S59-like
IPR007230 Nup98_auto-Pept-S59_dom
IPR036903 Nup98_auto-Pept-S59_dom_sf
IPR021967 Nup98_C

The S-nitrosylation sites of P49793

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 1026 PSRGDTAQEI C SPRLPISASH   
2 1067 FLSPSASVQE C RTPRTSSLMN   
3 1589 KAVRELLTRH C QLSETPESWA   
4 1609 AKETFLTQKL C VPAEWIHEAK   
5 1710 EMLHRIQQVD C SGYELEHLHT   
6 1734 SLCNRIEQIP C YNAKDRLAQS   
7 760 LAKITNEKGE C IVSDFTIGRK