UniprotKB/SwissProt ID: P49653 (P49653)
Gene Name:
P2rx2
Organism: Rattus norvegicus (Rat)
Function: ATP-gated nonselective transmembrane cation channel permeable to potassium, sodium and calcium (PubMed:10440098, PubMed:8961184, PubMed:9119082). Activation by extracellular ATP induces a variety of cellular responses, such as excitatory postsynaptic responses in sensory neurons, neuromuscular junctions (NMJ) formation, hearing, perception of taste and peristalsis. In the inner ear, regulates sound transduction and auditory neurotransmission, outer hair cell electromotility, inner ear gap junctions, and K(+) recycling. Mediates synaptic transmission between neurons and from neurons to smooth muscle (By similarity)
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Cell membrane
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