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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Signal recognition particle 9 kDa protein

UniprotKB/SwissProt ID: P49458 (P49458)

Gene Name: SRP9

Organism: Homo sapiens (Human)

Function: Component of the signal recognition particle (SRP) complex, a ribonucleoprotein complex that mediates the cotranslational targeting of secretory and membrane proteins to the endoplasmic reticulum (ER) (By similarity). SRP9 together with SRP14 and the Alu portion of the SRP RNA, constitutes the elongation arrest domain of SRP (PubMed:11089964). The complex of SRP9 and SRP14 is required for SRP RNA binding (By similarity)

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cytoplasm

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR009018 Signal_recog_particle_SRP9/14
IPR008832 SRP9
IPR039914 SRP9-like
IPR039432 SRP9_dom

The S-nitrosylation sites of P49458

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 39 LKYRHSDGNL C VKVTDDLVCL  CCCCCCHHHH H HHHHHHHCCC  3.02% 19483679
2 48 LCVKVTDDLV C LVYKTDQAQD  CCCCCCHHHH H HHHHHHHCCC  2.5% 19483679
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