Protein Name:
Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha
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UniprotKB/SwissProt ID: P49354 (P49354)
Gene Name:
FNTA
Organism: Homo sapiens (Human)
Function: Essential subunit of both the farnesyltransferase and the geranylgeranyltransferase complex. Contributes to the transfer of a farnesyl or geranylgeranyl moiety from farnesyl or geranylgeranyl diphosphate to a cysteine at the fourth position from the C-terminus of several proteins having the C-terminal sequence Cys-aliphatic-aliphatic-X. May positively regulate neuromuscular junction development downstream of MUSK via its function in RAC1 prenylation and activation
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization:
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Graphical Visualization of S-nitrosylation Sites:
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| InterPro ID |
Domain Name |
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IPR002088
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Prenyl_trans_a |
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The S-nitrosylation sites of P49354
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| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
341 |
EDILNKALEL C EILAKEKDTI |
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