Protein Name:
MARCKS-related protein
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UniprotKB/SwissProt ID: P49006 (P49006)
Gene Name:
MARCKSL1
Organism: Homo sapiens (Human)
Function: Controls cell movement by regulating actin cytoskeleton homeostasis and filopodium and lamellipodium formation (PubMed:22751924). When unphosphorylated, induces cell migration (By similarity). When phosphorylated by MAPK8, induces actin bundles formation and stabilization, thereby reducing actin plasticity, hence restricting cell movement, including neuronal migration (By similarity). May be involved in coupling the protein kinase C and calmodulin signal transduction systems (By similarity)
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Cytoplasm, cytoskeleton. Cell membrane
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Graphical Visualization of S-nitrosylation Sites:
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The S-nitrosylation sites of P49006
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| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
134 |
EEQEQGEIGA C SDEGTAQEGK |
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