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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Tryptophan 2,3-dioxygenase

UniprotKB/SwissProt ID: P48776 (P48776)

Gene Name: Tdo2

Organism: Mus musculus (Mouse)

Function: Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L-tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization:

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR037217 Trp/Indoleamine_2_3_dOase-like
IPR004981 Trp_2_3_dOase

The S-nitrosylation sites of P48776

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 266 EFRKQKEVLL C LFDEKRHDYL  CCCCCCCCCC C CCEEEECCCC  2.88% 22178444