Protein Name:
Sodium/calcium exchanger 2
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UniprotKB/SwissProt ID: P48768 (P48768)
Gene Name:
Slc8a2
Organism: Rattus norvegicus (Rat)
Function: Mediates the electrogenic exchange of Ca(2+) against Na(+) ions across the cell membrane, and thereby contributes to the regulation of cytoplasmic Ca(2+) levels and Ca(2+)-dependent cellular processes (PubMed:8021246, PubMed:9486131). Contributes to cellular Ca(2+) homeostasis in excitable cells (By similarity). Contributes to the rapid decrease of cytoplasmic Ca(2+) levels back to baseline after neuronal activation, and thereby contributes to modulate synaptic plasticity, learning and memory (By similarity). Plays a role in regulating urinary Ca(2+) and Na(+) excretion (By similarity)
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Cell membrane. Basolateral cell membrane. Perikaryon. Cell projection, dendrite. Cell projection, dendritic spine
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Graphical Visualization of S-nitrosylation Sites:
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The S-nitrosylation sites of P48768
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| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
537 |
FQDRLLHVSE C MGTVDVRVVR |
CCCHHHHHHH H HHCCCHHCCC |
2.07% |
22178444
16418269
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