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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Phosphatidylinositol transfer protein beta isoform

UniprotKB/SwissProt ID: P48739 (P48739)

Gene Name: PITPNB

Organism: Homo sapiens (Human)

Function: Catalyzes the transfer of phosphatidylinositol and phosphatidylcholine between membranes (PubMed:10531358, PubMed:18636990, PubMed:20332109). Also catalyzes the transfer of sphingomyelin (By similarity). Required for COPI-mediated retrograde transport from the Golgi to the endoplasmic reticulum; phosphatidylinositol and phosphatidylcholine transfer activity is essential for this function (PubMed:20332109)

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Golgi apparatus. Golgi apparatus membrane. Endoplasmic reticulum membrane

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR001666 PI_transfer
IPR055261 PI_transfer_N
IPR023393 START-like_dom_sf

The S-nitrosylation sites of P48739

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 13 LIKEFRVVLP C SVQEYQVGQL   
2 187 WKKELANSPD C PQMCAYKLVT   
3 191 LANSPDCPQM C AYKLVTIKFK   
4 94 HEKAWNAYPY C RTIVTNEYMK