UniprotKB/SwissProt ID: P48607 (P48607)
Gene Name:
spz
Organism: Drosophila melanogaster (Fruit fly)
Function: The activated form, spaetzle C-106, acts as a ligand for the Toll receptor (PubMed:12872120). Binding to Toll activates the Toll signaling pathway and induces expression of the antifungal peptide drosomycin (PubMed:8808632). Component of the extracellular signaling pathway that establishes dorsal-ventral polarity in the embryo (PubMed:11212919, PubMed:8124709)
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Secreted. Secreted. Secreted. Secreted. Secreted
|
|
|
