Protein Name:
Triosephosphate isomerase
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UniprotKB/SwissProt ID: P48500 (P48500)
Gene Name:
Tpi1
Organism: Rattus norvegicus (Rat)
Function: Triosephosphate isomerase is an extremely efficient metabolic enzyme that catalyzes the interconversion between dihydroxyacetone phosphate (DHAP) and D-glyceraldehyde-3-phosphate (G3P) in glycolysis and gluconeogenesis It is also responsible for the non-negligible production of methylglyoxal a reactive cytotoxic side-product that modifies and can alter proteins, DNA and lipids
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Cytoplasm
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Graphical Visualization of S-nitrosylation Sites:
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The S-nitrosylation sites of P48500
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| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
159 |
KAIADNVKDW C KVVLAYEPVW |
CCCCCCEEEC C CCCCCCCCCH |
3.25% |
19101475
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| 2 |
195 |
VHEKLRGWLK C NVSEGVAQCT |
CCCCCCEEEC C CCCCCCCCCH |
5.95% |
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| 3 |
204 |
KCNVSEGVAQ C TRIIYGGSVT |
CCCCCCEEEC C CCCCCCCCCH |
1.67% |
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| 4 |
21 |
GNWKMNGRKK C LGELICTLNA |
CCCCCCEEEC C CCCCCCCCCH |
7.09% |
16418269
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| 5 |
218 |
IYGGSVTGAT C KELASQPDVD |
CCCCCCEEEC C CCCCCCCCCH |
2.98% |
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| 6 |
27 |
GRKKCLGELI C TLNAAKLPAD |
CCCCCCEEEC C CCCCCCCCCH |
5.75% |
16418269
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| 7 |
42 |
AKLPADTEVV C APPTAYIDFA |
CCCCCCEEEC C CCCCCCCCCH |
5.93% |
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| 8 |
67 |
DPKIAVAAQN C YKVTNGAFTG |
CCCCCCEEEC C CCCCCCCCCH |
2.01% |
19101475
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