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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: 14-3-3-like protein G-BOX factor 14 lambda

UniprotKB/SwissProt ID: P48349 (P48349)

Gene Name: GRF6

Organism: Arabidopsis thaliana (Mouse-ear cress)

Function: Is associated with a DNA binding complex that binds to the G box, a well-characterized cis-acting DNA regulatory element found in plant genes (By similarity). Specific negative regulator of slow-vacuolar (SV) ion channel. Mediates F-actin dynamics possibly through inhibiting ADF1 phosphorylation (PubMed:26345162). Negative regulator of freezing tolerance that modulates cold-responsive C-repeat-binding factors (CBF) DREB1A and DREB1B proteins stability by facilitating their ubiquitin-mediated degradation when activated by CRPK1-mediated phosphorylation in freezing conditions; this processus is counteracted by B1L (PubMed:28344081, PubMed:31297122)

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Nucleus. Cell membrane. Cytoplasm

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR000308 14-3-3
IPR023409 14-3-3_CS
IPR036815 14-3-3_dom_sf
IPR023410 14-3-3_domain

The S-nitrosylation sites of P48349

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 103 SKVESELSSV C SGILKLLDSH