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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: LIM and senescent cell antigen-like-containing domain protein 1

UniprotKB/SwissProt ID: P48059 (P48059)

Gene Name: LIMS1

Organism: Homo sapiens (Human)

Function: Within the IPP (ILK-PINCH-PARVIN) complex, binds to F-actin, promoting F-actin bundling, a process required to generate force for actin cytoskeleton reorganization and subsequent dynamic cell adhesion events such as cell spreading and migration

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cell junction, focal adhesion. Cell membrane

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR047944 LIMS1/2-like_LIM1
IPR017351 PINCH-1-4-like
IPR047946 PINCH-1/2-like
IPR001781 Znf_LIM

The S-nitrosylation sites of P48059

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 138 RGLGKYICQK C HAIIDEQPLI   
2 281 WCVNCFACST C NTKLTLKNKF   
3 97 NNSWHPECFR C DLCQEVLADI