Protein Name:
Melatonin receptor type 1A
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UniprotKB/SwissProt ID: P48039 (P48039)
Gene Name:
MTNR1A
Organism: Homo sapiens (Human)
Function: High affinity receptor for melatonin. Likely to mediate the reproductive and circadian actions of melatonin. The activity of this receptor is mediated by pertussis toxin sensitive G proteins that inhibit adenylate cyclase activity. Possibly involved in sleep induction, by melatonin activation of the potassium channel KCNMA1/BK and the dissociation of G-beta and G-gamma subunits, thereby decreasing synaptic transmission (By similarity)
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Cell membrane
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Graphical Visualization of S-nitrosylation Sites:
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The S-nitrosylation sites of P48039
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| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
127 |
NITGIAINRY C YICHSLKYDK |
CCCCCCCCCC C CCCCCCCCCC |
1.34% |
22178444
15978051
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| 2 |
130 |
GIAINRYCYI C HSLKYDKLYS |
CCCCCCCCCC C CCCCCCCCCC |
0.47% |
22178444
15978051
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