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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Aldehyde dehydrogenase, mitochondrial

UniprotKB/SwissProt ID: P47738 (P47738)

Gene Name: Aldh2

Organism: Mus musculus (Mouse)

Function: Required for clearance of cellular formaldehyde, a cytotoxic and carcinogenic metabolite that induces DNA damage

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Mitochondrion matrix

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR016161 Ald_DH/histidinol_DH
IPR016163 Ald_DH_C
IPR016160 Ald_DH_CS_CYS
IPR029510 Ald_DH_CS_GLU
IPR016162 Ald_DH_N
IPR015590 Aldehyde_DH_dom

The S-nitrosylation sites of P47738

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 181 SYTRHEPVGV C GQIIPWNFPL  CCHHHHHHHH C CHHHHHHHHH  2.46% 21278135
2 321 FALFFNQGQC C CAGSRTFVQE  CCHHHHHHHH C CHHHHHHHHH  1.05% 22178444
16242127
3 388 SGQQEGAKLL C GGGAAADRGY  CCHHHHHHHH C CHHHHHHHHH  7.44% 22178444
21278135
4 68 TVNPSTGEVI C QVAEGNKEDV  CCHHHHHHHH C CHHHHHHHHH  3% 22178444
19483679
21278135