Protein Name:
Rabphilin-3A
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UniprotKB/SwissProt ID: P47708 (P47708)
Gene Name:
Rph3a
Organism: Mus musculus (Mouse)
Function: Plays an essential role in docking and fusion steps of regulated exocytosis (By similarity). At the presynaptic level, RPH3A is recruited by RAB3A to the synaptic vesicle membrane in a GTP-dependent manner where it modulates synaptic vesicle trafficking and calcium-triggered neurotransmitter release (By similarity). In the post-synaptic compartment, forms a ternary complex with GRIN2A and DLG4 and regulates NMDA receptor stability. Also plays a role in the exocytosis of arginine vasopressin hormone (By similarity)
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane. Cell projection, dendritic spine. Postsynaptic cell membrane. Membrane
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Graphical Visualization of S-nitrosylation Sites:
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The S-nitrosylation sites of P47708
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| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
641 |
IGKSNDYIGG C QLGISAKGER |
CCCCCCCCCC C CCCCCCCCCC |
2.26% |
22588120
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