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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Small ribosomal subunit protein uS7

UniprotKB/SwissProt ID: P46782 (P46782)

Gene Name: RPS5

Organism: Homo sapiens (Human)

Function: Component of the small ribosomal subunit (PubMed:23636399). The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell (PubMed:23636399). Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome (PubMed:34516797)

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cytoplasm. Nucleus, nucleolus

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR000235 Ribosomal_uS7
IPR020606 Ribosomal_uS7_CS
IPR023798 Ribosomal_uS7_dom
IPR036823 Ribosomal_uS7_dom_sf
IPR005716 Ribosomal_uS7_euk/arc

The S-nitrosylation sites of P46782

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 155 RRVNQAIWLL C TGAREAAFRN  CCCCCCCCCC C CCCCCEEEEC  2.86% 22178444
18335467
2 172 AFRNIKTIAE C LADELINAAK  CCCCCCCCCC C CCCCCEEEEC  2.54% 18335467
19483679
25040305
22178444
3 66 YAAKRFRKAQ C PIVERLTNSM  CCCCCCCCCC C CCCCCEEEEC  2.72%