Protein Name:
26S proteasome regulatory subunit 7
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UniprotKB/SwissProt ID: P46471 (P46471)
Gene Name:
Psmc2
Organism: Mus musculus (Mouse)
Function: Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair. PSMC2 belongs to the heterohexameric ring of AAA (ATPases associated with diverse cellular activities) proteins that unfolds ubiquitinated target proteins that are concurrently translocated into a proteolytic chamber and degraded into peptides
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Cytoplasm
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Graphical Visualization of S-nitrosylation Sites:
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The S-nitrosylation sites of P46471
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| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
377 |
DIRFELLARL C PNSTGAEIRS |
CCCCCCCCHH C CCCHHCCCCC |
2.21% |
21278135
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| 2 |
389 |
NSTGAEIRSV C TEAGMFAIRA |
CCCCCCCCHH C CCCHHCCCCC |
2.76% |
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