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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Vesicle-fusing ATPase

UniprotKB/SwissProt ID: P46460 (P46460)

Gene Name: Nsf

Organism: Mus musculus (Mouse)

Function: Required for vesicle-mediated transport. Catalyzes the fusion of transport vesicles within the Golgi cisternae. Is also required for transport from the endoplasmic reticulum to the Golgi stack. Seems to function as a fusion protein required for the delivery of cargo proteins to all compartments of the Golgi stack GRIA2 leads to influence GRIA2 membrane cycling (By similarity)

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cytoplasm

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR003593 AAA+_ATPase
IPR041569 AAA_lid_3
IPR009010 Asp_de-COase-like_dom_sf
IPR003959 ATPase_AAA_core
IPR003960 ATPase_AAA_CS
IPR004201 Cdc48_dom2
IPR029067 CDC48_domain_2-like_sf
IPR003338 CDC4_N-term_subdom
IPR054419 NSF_ATPase_lid
IPR027417 P-loop_NTPase
IPR039812 Vesicle-fus_ATPase

The S-nitrosylation sites of P46460

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 11 MAGRTMQAAR C PTDELSLSNC  CCCCCCCCCC C CCCCCCCCCC  3.5% 22588120
2 21 CPTDELSLSN C AVVNEKDFQS  CCCCCCCCCC C CCCCCCCCCC  2.46% 22588120
3 250 FPPEIVEQMG C KHVKGILLYG  CCCCCCCCCC C CCCCCCCCCC  2.01% 16418269
4 264 KGILLYGPPG C GKTLLARQIG  CCCCCCCCCC C CCCCCCCCCC  6.61% 16418269
19101475
5 568 EESNFPFIKI C SPDKMIGFSE  CCCCCCCCCC C CCCCCCCCCC  4.03%
6 59 LRTHPSVVPG C IAFSLPQRKW  CCCCCCCCCC C CCCCCCCCCC  1.33%
7 599 FDDAYKSQLS C VVVDDIERLL  CCCCCCCCCC C CCCCCCCCCC  3.51% 22588120