Protein Name:
Cofilin-2
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UniprotKB/SwissProt ID: P45591 (P45591)
Gene Name:
Cfl2
Organism: Mus musculus (Mouse)
Function: Controls reversibly actin polymerization and depolymerization in a pH-sensitive manner. It has the ability to bind G- and F-actin in a 1:1 ratio of cofilin to actin. It is the major component of intranuclear and cytoplasmic actin rods. Required for muscle maintenance. May play a role during the exchange of alpha-actin forms during the early postnatal remodeling of the sarcomere
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Nucleus matrix. Cytoplasm, cytoskeleton
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Graphical Visualization of S-nitrosylation Sites:
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The S-nitrosylation sites of P45591
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| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
39 |
IKKRKKAVLF C LSDDKRQIIV |
CCCCCEECHH H HHHHCCCCCC |
2.88% |
21278135
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| 2 |
80 |
SFVKLLPLND C RYALYDATYE |
CCCCCEECHH H HHHHCCCCCC |
3.31% |
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