Protein Name:
Cysteine proteinase RD21A
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UniprotKB/SwissProt ID: P43297 (P43297)
Gene Name:
RD21A
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Cysteine protease that plays a role in immunity, senescence, and biotic and abiotic stresses (Probable). Involved in immunity against the necrotrophic fungal pathogen Botrytis cinerea (PubMed:22238602). Involved in elicitor-stimulated programmed cell death (PCD). During infection by the necrotrophic fungal pathogen Botrytis cinerea, functions as a PCD-promoting protease that is released from the ER body or vacuole to the cytoplasm (PubMed:23398119). Accumulates in endoplasmic reticulum-derived bodies in epidermal cells and may participate in cell death in stressed or injured cells (PubMed:11577182). Involved in water stress-induced cell death through its protease activity that is released to the cytoplasm after vacuolar collapse (PubMed:26884487). Possesses protease activity in vitro and is involved in cell death in the transmitting tract and septum epidermis during flower development (PubMed:26160583). Possesses peptide ligase activity. Can ligate peptides to unmodified N-termini of acceptor proteins. Probably ligates through a thioester intermediate (PubMed:18660805)
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Vacuole. Golgi apparatus. Cytoplasm, Stress granule. Cytoplasm, P-body
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Graphical Visualization of S-nitrosylation Sites:
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The S-nitrosylation sites of P43297
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| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
233 |
DYPYKGVDGT C DQIRKNAKVV |
CCCCHHHHHH H HHHHHHHHHH |
4.42% |
22115780
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| 2 |
342 |
ARNIASSSGK C GIAIEPSYPI |
CCCCHHHHHH H HHHHHHHHHH |
5.63% |
22115780
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