Protein Name:
Cathepsin K
|
UniprotKB/SwissProt ID: P43235 (P43235)
Gene Name:
CTSK
Organism: Homo sapiens (Human)
Function: Thiol protease involved in osteoclastic bone resorption and may participate partially in the disorder of bone remodeling. Displays potent endoprotease activity against fibrinogen at acid pH. May play an important role in extracellular matrix degradation. Involved in the release of thyroid hormone thyroxine (T4) by limited proteolysis of TG/thyroglobulin in the thyroid follicle lumen (PubMed:11082042)
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Lysosome. Secreted. Apical cell membrane
|
|
|
Graphical Visualization of S-nitrosylation Sites:
|
|
The S-nitrosylation sites of P43235
|
| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
139 |
PVKNQGQCGS C WAFSSVGALE |
CCCCEEEEEH H HHHHHCHHHH |
1.52% |
22178444
10521264
|
|
