Protein Name:
Cyclin-dependent kinase inhibitor 2A
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UniprotKB/SwissProt ID: P42771 (P42771)
Gene Name:
CDKN2A
Organism: Homo sapiens (Human)
Function: Acts as a negative regulator of the proliferation of normal cells by interacting strongly with CDK4 and CDK6. This inhibits their ability to interact with cyclins D and to phosphorylate the retinoblastoma protein
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Cytoplasm. Nucleus
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Graphical Visualization of S-nitrosylation Sites:
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| InterPro ID |
Domain Name |
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IPR050776
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Ank_Repeat/CDKN_Inhibitor |
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IPR036770
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Ankyrin_rpt-contain_sf |
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The S-nitrosylation sites of P42771
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| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
72 |
LLLLHGAEPN C ADPATLTRPV |
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