UniprotKB/SwissProt ID: P42532 (P42532)
Gene Name:
SLN
Organism: Oryctolagus cuniculus (Rabbit)
Function: Reversibly inhibits the activity of ATP2A1/SERCA1 and ATP2A2/SERCA2 in sarcoplasmic reticulum by decreasing the apparent affinity of the ATPase for Ca(2+) (PubMed:23362265, PubMed:9575189). Also inhibits the activity of ATP2A3/SERCA3 (By similarity). Modulates calcium re-uptake during muscle relaxation and plays an important role in calcium homeostasis in muscle (PubMed:23362265, PubMed:9575189). Required for muscle-based, non-shivering thermogenesis (By similarity)
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Sarcoplasmic reticulum membrane. Endoplasmic reticulum membrane
|
|
|
