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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Lamina-associated polypeptide 2, isoform alpha

UniprotKB/SwissProt ID: P42166 (P42166)

Gene Name: TMPO

Organism: Homo sapiens (Human)

Function: May be involved in the structural organization of the nucleus and in the post-mitotic nuclear assembly. Plays an important role, together with LMNA, in the nuclear anchorage of RB1 TP and TP5 may play a role in T-cell development and function. TP5 is an immunomodulating pentapeptide

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Nucleus. Chromosome

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR021623 LAP2alpha_C
IPR013146 LEM-like_dom
IPR011015 LEM/LEM-like_dom_sf
IPR003887 LEM_dom
IPR051656 LEM_domain

The S-nitrosylation sites of P42166

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 280 LASERNLFIS C KSSHDRCLEK   
2 330 GYYKDIVENI C GREKSGIQPL   
3 341 GREKSGIQPL C PERSHISDQS   
4 518 QVDRQLPSLA C KYPVSSREAT   
5 561 GGIQAASTES C NQQLDLALCR   
6 629 SKTYDAASYI C EAAFDEVKMA   
7 684 KGGTLFGGEV C KVIKKRGNKH