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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Indolethylamine N-methyltransferase

UniprotKB/SwissProt ID: P40936 (P40936)

Gene Name: Inmt

Organism: Mus musculus (Mouse)

Function: Catalyzes the N-methylation of tryptamine and structurally related compounds (By similarity). Functions as a thioether S-methyltransferase and is active with a variety of thioethers and the corresponding selenium and tellurium compounds, including 3-methylthiopropionaldehyde, dimethyl selenide, dimethyl telluride, 2-methylthioethylamine, 2-methylthioethanol, methyl-n-propyl sulfide and diethyl sulfide. Plays an important role in the detoxification of selenium compounds

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cytoplasm

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR025820 NNMT/PNMT/TEMT_CS
IPR000940 NNMT_TEMT_trans
IPR053384 SAM-dep_methyltransferase
IPR029063 SAM-dependent_MTases_sf

The S-nitrosylation sites of P40936

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 231 VVEKAIQDAG C QVLKCNCVSL  CCCEEEECCC C CCCCCCCHHH  2.44% 21278135