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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Peroxisomal biogenesis factor 19

UniprotKB/SwissProt ID: P40855 (P40855)

Gene Name: PEX19

Organism: Homo sapiens (Human)

Function: Necessary for early peroxisomal biogenesis. Acts both as a cytosolic chaperone and as an import receptor for peroxisomal membrane proteins (PMPs). Binds and stabilizes newly synthesized PMPs in the cytoplasm by interacting with their hydrophobic membrane-spanning domains, and targets them to the peroxisome membrane by binding to the integral membrane protein PEX3. Excludes CDKN2A from the nucleus and prevents its interaction with MDM2, which results in active degradation of TP53

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cytoplasm. Peroxisome membrane

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR006708 Pex19
IPR038322 Pex19_C_sf

The S-nitrosylation sites of P40855

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 128 DMTSQQEFTS C LKETLSGLAK