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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Adenylyl cyclase-associated protein 1

UniprotKB/SwissProt ID: P40124 (P40124)

Gene Name: Cap1

Organism: Mus musculus (Mouse)

Function: Directly regulates filament dynamics and has been implicated in a number of complex developmental and morphological processes, including mRNA localization and the establishment of cell polarity

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cell membrane

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR001837 Adenylate_cyclase-assoc_CAP
IPR013912 Adenylate_cyclase-assoc_CAP_C
IPR013992 Adenylate_cyclase-assoc_CAP_N
IPR017901 C-CAP_CF_C-like
IPR016098 CAP/MinC_C
IPR036223 CAP_C_sf
IPR028417 CAP_CS_C
IPR018106 CAP_CS_N
IPR053950 CAP_N
IPR036222 CAP_N_sf
IPR006599 CARP_motif

The S-nitrosylation sites of P40124

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 29 EAVSHTSDMH C GYGDSPSKGA  CHHHHHHHHH H HHHHHHHHHH  3.45% 21278135
2 355 ELKQVAYIYK C VNTTLQIKGK  CHHHHHHHHH H HHHHHHHHHH  1.28%
3 374 GKINSITVDN C KKLGLVFDDV  CHHHHHHHHH H HHHHHHHHHH  3.39%
4 415 PTISINKTDG C HAYLSKNSLD  CHHHHHHHHH H HHHHHHHHHH  1.52% 21278135
5 426 HAYLSKNSLD C EIVSAKSSEM  CHHHHHHHHH H HHHHHHHHHH  4.69%
6 92 ERALLATASQ C QQPAGNKLSD  CHHHHHHHHH H HHHHHHHHHH  3.62% 21278135