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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: DNA-binding protein SMUBP-2

UniprotKB/SwissProt ID: P38935 (P38935)

Gene Name: IGHMBP2

Organism: Homo sapiens (Human)

Function: 5' to 3' helicase that unwinds RNA and DNA duplexes in an ATP-dependent reaction (PubMed:19158098, PubMed:22999958, PubMed:30218034). Specific to 5'-phosphorylated single-stranded guanine-rich sequences (PubMed:22999958, PubMed:8349627). May play a role in RNA metabolism, ribosome biogenesis or initiation of translation (PubMed:19158098, PubMed:19299493). May play a role in regulation of transcription (By similarity). Interacts with tRNA-Tyr (PubMed:19299493)

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Nucleus. Cytoplasm. Cell projection, axon

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR003593 AAA+_ATPase
IPR035896 AN1-like_Znf
IPR050534 Coronavir_polyprotein_1ab
IPR041679 DNA2/NAM7-like_C
IPR041677 DNA2/NAM7_AAA_11
IPR014001 Helicase_ATP-bd
IPR027417 P-loop_NTPase
IPR001374 R3H_dom
IPR036867 R3H_dom_sf
IPR034072 R3H_Smubp-2
IPR047187 SF1_C_Upf1
IPR004483 SMUBP-2/Hcs1-like
IPR048761 SMUBP-2_HCS1_1B
IPR000058 Znf_AN1

The S-nitrosylation sites of P38935

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 496 VPLLLVDTAG C GLFELEEEDE