UniprotKB/SwissProt ID: P38484 (P38484)
Gene Name:
IFNGR2
Organism: Homo sapiens (Human)
Function: Associates with IFNGR1 to form a receptor for the cytokine interferon gamma (IFNG) (PubMed:7615558, PubMed:7673114, PubMed:8124716). Ligand binding stimulates activation of the JAK/STAT signaling pathway (PubMed:15356148, PubMed:7673114, PubMed:8124716). Required for signal transduction in contrast to other receptor subunit responsible for ligand binding (PubMed:7673114)
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Cell membrane. Cytoplasmic vesicle membrane. Golgi apparatus membrane. Endoplasmic reticulum membrane. Cytoplasm
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