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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: DNA-directed RNA polymerase II subunit RPB9

UniprotKB/SwissProt ID: P36954 (P36954)

Gene Name: POLR2I

Organism: Homo sapiens (Human)

Function: Core component of RNA polymerase II (Pol II), a DNA-dependent RNA polymerase which synthesizes mRNA precursors and many functional non-coding RNAs using the four ribonucleoside triphosphates as substrates. Pol II is the central component of the basal RNA polymerase II transcription machinery. It is composed of mobile elements that move relative to each other. POLR2I/RPB9 is part of the upper jaw surrounding the central large cleft and thought to grab the incoming DNA template

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Nucleus, nucleolus

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR019761 DNA-dir_RNA_pol-M_15_CS
IPR012164 Rpa12/Rpb9/Rpc10/TFS
IPR001529 Zn_ribbon_RPB9
IPR034012 Zn_ribbon_RPB9_C
IPR001222 Znf_TFIIS

The S-nitrosylation sites of P36954

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 52 CDYQQEADNS C IYVNKITHEV