Protein Name:
Bone morphogenetic protein receptor type-1B
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UniprotKB/SwissProt ID: P36898 (P36898)
Gene Name:
Bmpr1b
Organism: Mus musculus (Mouse)
Function: On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for BMP7/OP-1. Receptor for GDF5 (PubMed:19229295, PubMed:26105076). Positively regulates chondrocyte differentiation through GDF5 interaction (PubMed:24098149)
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Cell membrane
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Graphical Visualization of S-nitrosylation Sites:
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