UniprotKB/SwissProt ID: P35951 (P35951)
Gene Name:
Ldlr
Organism: Mus musculus (Mouse)
Function: Binds low density lipoprotein /LDL, the major cholesterol-carrying lipoprotein of plasma, and transports it into cells by endocytosis. In order to be internalized, the receptor-ligand complexes must first cluster into clathrin-coated pits. Forms a ternary complex with PGRMC1 and TMEM97 receptors which increases LDLR-mediated LDL internalization
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Cell membrane. Membrane, clathrin-coated pit. Golgi apparatus. Early endosome. Late endosome. Lysosome
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