Protein Name:
Hydroxymethylglutaryl-CoA lyase, mitochondrial
|
UniprotKB/SwissProt ID: P35914 (P35914)
Gene Name:
HMGCL
Organism: Homo sapiens (Human)
Function: Mitochondrial 3-hydroxy-3-methylglutaryl-CoA lyase that catalyzes a cation-dependent cleavage of (S)-3-hydroxy-3-methylglutaryl-CoA into acetyl-CoA and acetoacetate, a key step in ketogenesis. Terminal step in leucine catabolism. Ketone bodies (beta-hydroxybutyrate, acetoacetate and acetone) are essential as an alternative source of energy to glucose, as lipid precursors and as regulators of metabolism
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Mitochondrion matrix. Peroxisome
|
|
|
Graphical Visualization of S-nitrosylation Sites:
|
|
The S-nitrosylation sites of P35914
|
| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
323 |
KTSSKVAQAT C KL-------- |
|
|
|
|
