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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Glutaredoxin-1

UniprotKB/SwissProt ID: P35754 (P35754)

Gene Name: GLRX

Organism: Homo sapiens (Human)

Function: Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cytoplasm

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR011767 GLR_AS
IPR047185 GLRX1
IPR002109 Glutaredoxin
IPR011899 Glutaredoxin_euk/vir
IPR014025 Glutaredoxin_subgr
IPR036249 Thioredoxin-like_sf

The S-nitrosylation sites of P35754

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 79 TVPRVFIGKD C IGGCSDLVSL  CCCCCCCCEE C CCCEEEEECC  3.38% 22178444
17355958
2 8 ---MAQEFVN C KIQPGKVVVF  CCCCCCCCEE C CCCEEEEECC  3.27% 22178444
17355958
3 83 VFIGKDCIGG C SDLVSLQQSG  CCCCCCCCEE C CCCEEEEECC  2.11% 22178444
17355958